Pluto Bioinformatics

HEXIM1 is induced by DHODH inhibition to suppress melanoma [Gro-Seq] (GSE57430)

Bulk RNA sequencing

Our study illustrates that HEXIM1 is a tumor suppressor that responds to cell stress, consequently inhibiting productive elongation of proliferative genes in melanoma. SOURCE: Leonard Zon (zon@enders.tch.harvard.edu) - Boston Children's Hospital