Pluto Bioinformatics

GSE109324: Single cell RNA-seq of long-term hematopoietic stem cells (LT-HSCs) and common myeloid progenitors (CMPs)

Bulk RNA sequencing

We aimed to reseach the differences between IL4R high and low expression LT-HSC/CMP,our data revealed distinct sensitivities of HSCs and common myeloid progenitors (CMPs) to IL4-induced apoptosis, and IL4Rahigh HSCs were more susceptible to unfolded protein response (UPR) and irradiation-induced apoptosis. SOURCE: Caiying Zhu (zhucaiying@ihcams.ac.cn) - Institute of Hematology & Blood Diseases Hospital

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