Pluto Bioinformatics

GSE142867: HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [RNA-seq]

Bulk RNA sequencing

We performed RNA-sequencing on erythropoietic cells cultured in normoxia or hypoxia at days 3,7, and 10. We found numerous expression changes induced by hypoxia, including the canonical hypoxia targets as well as a number of genes encoding genes involved in epigenetic processes. SOURCE: Lucy Godley (lgodley@medicine.bsd.uchicago.edu) - University of Chicago