Pluto Bioinformatics

GSE128380: Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain

Bulk RNA sequencing

Rett syndrome is an X-linked neurodevelopmental disorder caused by mutation in the methyl-CpG-binding protein 2 gene in the majority of cases. We describe an RNA sequencing dataset of postmortem brain tissue samples from four females clinically diagnosed with Rett syndrome and four age-matched female donors. The dataset contains transcriptomes from two brain regions, temporal and cingulate cortex, for each individual, providing a valuable resource to explore the biology of the human brain in Rett syndrome. SOURCE: Kimberly,A,Aldinger (kimberly.aldinger@seattlechildrens.org) - Seattle Children's Research Institute