We demonstrated that the offspring of depressed fathers display reduced resilience to stress and enhanced susceptibility to depression. To explain the observed behavioural phenotypes of depression in offspring produced by depressed fathers, molecular profiling was performed in key brain regions.We examined the hippocampal sample from normal male mice, stress induced depressive male mice and  male offspring born to stress-induced depressed male mice by RNA sequencing. SOURCE: Zhen Zhou (darknesszhou@gmail.com) -  Nanjing University

GSE133494: RNA sequencing of hippocampal sample from normal male mice, stress induced depressive male mice and  male offspring born to stress-induced depressed male mice

Pluto Bioinformatics

GSE133494: RNA sequencing of hippocampal sample from normal male mice, stress induced depressive male mice and male offspring born to stress-induced depressed male mice