Pluto Bioinformatics

GSE116894: RNA-sequencing of Control and TLE3-deficient Beige Adipocytes

Bulk RNA sequencing

Prolonged cold exposure stimulates the recruitment of beige adipocytes within white adipose tissue. Beige adipocytes depend on mitochondrial oxidative phosphorylation to drive thermogenesis. The transcriptional coregulator TLE3 inhibits mitochondrial and metabolic gene expression in beige adipocytes. SOURCE: Stephanie PearsonClaudio Villanueva University of Utah