Pluto Bioinformatics

GSE74985: Hipposeq: an RNA-seq based atlas of gene expression in excitatory hippocampal neurons

Bulk RNA sequencing

Here, we used next-generation RNA sequencing (RNA-seq) to produce a quantitative, whole genome atlas of gene expression for every excitatory neuronal class in the hippocampus; namely, granule cells and mossy cells of the dentate gyrus, and pyramidal cells of areas CA3, CA2, and CA1. Moreover, for the canonical neurons of the trisynaptic loop, we profiled transcriptomes at both dorsal and ventral poles, producing a cell class- and region-specific transcriptional atlas for these canonical populations. SOURCE: Mark,Steven,CembrowskiNelson Spruston Howard Hughes Medical Institute