Pluto Bioinformatics

GSE121904: Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing

Bulk RNA sequencing

This analysis represents the first comprehensive sampling of germ cells in the developing testis over time, at high-resolution, single-cell depth. From these analyses, we have not only revealed novel genetic regulatory signatures of murine germ cells over time, but have also demonstrated that cell types positive for a single marker gene have the capacity to change dramatically during testis maturation, and therefore cells of a particular identity may differ significantly from postnatal to adult life. SOURCE: Jennifer,K,GrenierBiotechnology Building rm 333 Cornell University