We conduct transcriptome comparison of lumianl breast cancer cells and basal cells to gain genomic insights on the biological processes. More than 3000 known genes were found changed in basal breast cancer cells. Ingenuity Pathway Analysis _IPA_ and Gene Set Enrichment Analysis _GSEA_ show that the prominent altered pathways in basal cells are related to regulation of actin-based motility, JAK/STAT3 signaling pathway. SOURCE: Lixing Zhan (lxzhan@sibs.ac.cn) - Laboratory of cell polarity & cancer metabolism Shanghai Institute for Biological Sciences, Chinese Academy of Sciences

Pluto Bioinformatics

GSE110810: RNA sequencing Facilitates Quantitative Analysis of luminal breast cancer cells and basal breast cancer cells Transcriptomes