GATA1 is repressed in hematopoietic stem cells. To understand the significance of Gata1 gene silencing in HSC  we generated GATA1-HSC overexpressing mice (MG-G1). RNA-seq was performed to analyze the gene expression profiles between MG-G1 and WT adult bone marrow LSK cells to examine the consequence of GATA1 overexpression upon HSC. SOURCE: Lei YU (yulei@med.tohoku.ac.jp) - Medical Biochemistry Tohoku University School of Medicine

Pluto Bioinformatics

GSE85750: Comparison of expression profiles between WT and MG-G1 adult bone marrow LSK cells