Pluto Bioinformatics

GSE108341: ICAMs are not obligatory for functional immune synapses between nave CD4 T cells and lymph node DCs

Bulk RNA sequencing

The quantitative deep bulk MARS-seq analysis demonstrated that DCs from ICAM-1/2 double knockout (DKO) chimeric LNs display similar transcriptomes to those of WT DCs in both their resting and CD40 mAb activated states. SOURCE: Dena Leshkowitz (dena.leshkowitz@weizmann.ac.il) - Weizmann Institute of Science