Pluto Bioinformatics

GSE139090: Age-associated Changes in the Transcriptome of SCA7 Mice

Bulk RNA sequencing

Atxn7 repeat expansion mutations lead to ataxia phenotypes. Total cerebellar RNA from mice with normal Atxn7 repeat lengths and expanded repeats (92 CAG) were sequenced to compared gene expression changes at 12 and 29 weeks of age in normal vs. expanded repeats. SOURCE: Theresa Gaasterland (tgaasterland@ucsd.edu) - Laboratory of Computational Genomics University of California San Diego