Pluto Bioinformatics

MV4;11 cells post-treatment with either DMSO, OICR-942, MS67, or MS67N (GSE150554)

Bulk RNA sequencing

Examination of transcriptome profiles in MV4;11 cells post-treatment with either DMSO, OICR-9429 (a small molecule designed to interfere with WDR5 binding to MLL), MS67 (a WDR5-specific PROTAC/degrader) or MS67N (a MS67 analog control incapable of E3 ligand conjugation).