Pluto Bioinformatics

GSE145012: Transcriptional profiling of germ-free and conventionalized mouse liver

Bulk RNA sequencing

The microbiome has been shown to have significant effects on susceptibility to liver disease. How the microbiome affects hepatic signaling pathways to mechanistically mediate these responses is unknown. Utilizing germ-free and conventionalized (microbiome-replete) mice, we characterized the effects of having a microbiome on the hepatic transcriptome. SOURCE: Bejan Saeedi (bejansaeedi@gmail.com) - Neish Emory University