Pluto Bioinformatics

GSE142535: Therapeutic IDOL reduction ameliorates amyloidosis and improves cognitive function in APP/PS1 mice

Bulk RNA sequencing

An antisense oligonucleotide (ASO) against E3 ubiquitin ligase IDOL in the brain significantly decreased A pathology, and improved spatial learning and memory in APP/PS1 mice. SOURCE: Russell Littman (rlittman16@g.ucla.edu) - Yang Lab UCLA