Pluto Bioinformatics

GSE144961: Circadian Cryptochrome 1 (CRY1) Rhythmically Modulates the DNA Damage Response [RNA-seq]

Bulk RNA sequencing

These studies identify a novel node of AR-regulated DNA repair through CRY1 directly regulating HR-mediated DNA repair to enhance cancer progression and discern a potential avenue to be targeted in late stage disease to improve patient outcome. SOURCE: Ayesha Shafi (ayesha.shafi@jefferson.edu) - Thomas Jefferson University